The domain within your query sequence starts at position 193 and ends at position 469; the E-value for the 3qwe domain shown below is 5e-41.

ELDNLLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIG
IQEFMPLQSLFTNALLSDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKDLWK
QQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLAKNLNKQLEKRR
RLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNL
FHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKA

This is a PDB domain - please see the PDBSUM entry of 3qwe for further annotation